Un procent alarmant de 47% dintre oameni nu pot adromi sau chiar r\u0103m\u00e2n treji peste noapte. F\u0103r\u0103 odihn\u0103 corespunz\u0103toare organismul prezint\u0103 semne clare de stres, fiind afectate dispozi\u021bia, concentrarea, sistemul imunitar \u0219i capacitatea de detoxifiere \u0219i regenerare a organismului. Acidul gamma aminobutiric (GABA)<\/strong>\u00a0este un aminoacid produs \u00een mod natural \u00een creier. GABA func\u021bioneaz\u0103 ca un neurotransmi\u021b\u0103tor, facilit\u00e2nd comunicarea \u00eentre celulele creierului. Rolul cel mai important al GABA \u00een organism este de a reduce hiperactivitatea neuronal\u0103 \u0219i a sistemului nervos central. GABA are, de asemenea, un rol important \u00een men\u021binerea tonusului muscular. Al\u0103turi de glutamat, cel mai important neurotransmi\u021b\u0103tor excitator al organismului, GABA reprezint\u0103 un factor decisiv al homeostaziei sau echilibrului fizic \u0219i mintal al corpului.<\/p>\n GABA regleaz\u0103 neurotransmi\u021b\u0103torii noradrenalin\u0103, dopanim\u0103 \u0219i serotonin\u0103<\/strong>, put\u00e2nd facilita schimbarea din \u00eengrijorare \u00een relaxare, iar triste\u021bea \u00een stare de bine. Dac\u0103 nivelurile GABA din organism sunt mici, se instaleaz\u0103 starea de anxietate, tensiune, depresie \u0219i insomnie [1].<\/p>\n Prin inhibarea activit\u0103\u021bii neuronale, GABA \u00eembun\u0103t\u0103\u021be\u0219te somnul, reduce stresul mintal \u0219i fizic, scade anxietatea \u0219i ajut\u0103 la recuperarea st\u0103rii de calm. GABA permite corpului \u0219i min\u021bii s\u0103 se relaxeze \u0219i s\u0103 doarm\u0103 profund pe tot parcursul nop\u021bii. Activitatea sc\u0103zut\u0103 a GABA este asociat\u0103 cu insomnia \u0219i tulbur\u0103rile de somn. Studiile arat\u0103 c\u0103 nivelurile de GABA la persoanele cu insomnie sunt cu aproape 30% mai mici dec\u00e2t la persoanele f\u0103r\u0103 tulbur\u0103ri de somn. De asemenea, nivelurile sc\u0103zute ale GABA sunt asociate cu un somn nelini\u0219tit, cu treziri dese.<\/p>\n Slaba calitate a somnului este asociat\u0103 cu tensiuna arterial\u0103 m\u0103rit\u0103, pofta de dulce \u0219i m\u00e2nc\u0103ruri procesate, cre\u0219terea \u00een greutate, diabetul, atacul de cord \u0219i accidentul vascular cerebrale.<\/p>\n Alcoolul imit\u0103 efectele GABA prin legarea de receptorii GABA din creier. Studiile au ar\u0103tat c\u0103 alcoolul nu cre\u0219te nivelul GABA, dar produce efecte similare asupra organismului,\u00a0cu<\/strong>\u00a0repercusiuni dezastruoase pe termen lung<\/strong>.<\/p>\n Expunerea repetat\u0103 la alcool poate desensibiliza receptorii GABA [2]. Aceast\u0103 desensibilizare poate determina st\u0103ri de stres sau de anxietate crescut\u0103, ceea ce m\u0103re\u0219te dorin\u021ba, frecven\u021ba \u0219i cantitatea de alcool consumat.<\/p>\n Desensibilizarea receptorilor GABA, datorat\u0103 consumului repetat de alcool, se observ\u0103 prin simptomele de sevraj (st\u0103ri de anxietate \u0219i drepresie \u00een timpul perioadei de abstinen\u021b\u0103). Creierul poate deveni supra-stimulat \u0219i incapabil s\u0103 regleze singur nivelul GABA, declan\u0219\u00e2nd astfel simptome de sevraj.<\/p>\n Studii precum acesta<\/strong>\u00a0(HTTPS:\/\/WWW.NATURE.COM\/ARTICLES\/NPP2011216<\/a>) [3] arat\u0103 c\u0103 acidul gamma aminobutiric produce rezultate promi\u021b\u0103toare \u00een tratamentul dependen\u021belor de alcool, nicotin\u0103 \u0219i droguri.<\/p>\n 7 din 10 oameni prezint\u0103 deficien\u021b\u0103 de magneziu, unul dintre cei mai importan\u021bi nutrien\u021bi de care are nevoie corpul uman. S-a demonstrat c\u0103 magneziul moduleaz\u0103 activitatea GABA din creier [4], ac\u021bion\u00e2nd asupra receptorilor GABA pentru a facilita neurotransmisia GABA \u0219i instalarea efectelor de relaxare asupra sistemului nervos central.<\/p>\n Lipsa repetat\u0103 de somn produce multe dezechilibre \u00een organism, inclusiv sc\u0103derea rapid\u0103 a nivelului de magneziu, mineral implicat \u00een peste 300 de reac\u021bii enzimatice \u0219i \u00een mai mult de 600 de reac\u021bii celulare. Magneziul este un mineral deosebit de important \u00een func\u021bionarea sistemului nervos \u0219i tot mai multe studii arat\u0103 c\u0103 deficien\u021ba de magneziu (hipomagneziemia) poate s\u0103 genereze boli mintale, precum depresiile majore \u0219i dependen\u021ba. Lipsa de magneziu poate genera o stare de nervozitate, iritabilitate \u0219i agresivitate.<\/strong><\/p>\n Magneziul<\/strong>\u00a0este necesar \u00een transmiterea impulsurilor nervoase, a func\u021bion\u0103rii normale a mu\u0219chilor, sinteza proteinelor, controlul glicemiei, reglarea tensiunii arteriale \u0219i a ritmului cardiac,\u00a0cu rol esen\u021bial \u00een producerea ADN-ului<\/strong>\u00a0\u0219i<\/strong>\u00a0transformarea alimentelor \u00een energie<\/strong>.<\/p>\n Caren\u021ba de magneziu genereaz\u0103 simptome care includ dureri musculare, crampe, spasme, circula\u021bie periferic\u0103 deficitar\u0103 (extremit\u0103\u021bi reci), insomnie \u0219i anxietate<\/p>\n Mai multe informa\u021bii despre magneziu \u00een form\u0103 lipozomal\u0103 natural\u0103 sunt disponibile aici:\u00a0LIPOZOMAL MAGNEZIU\u00a0<\/strong>HYPERNATURA<\/strong>\u00ae<\/strong><\/a><\/p>\n Melatonina este o molecul\u0103 aproape identic\u0103 cu serotonina, iar rolul principal \u00een creier este de a regla somnul \u0219i ritmul circadian. Un simptom al deficien\u021bei de melatonin\u0103 este incapacitatea de a adormi dup\u0103 trezirea din somn pe timpul nop\u021bii.<\/p>\n Studiul clinic publicat \u00een\u00a0PubMed<\/strong>\u00a0(HTTPS:\/\/WWW.NCBI.NLM.NIH.GOV\/PMC\/ARTICLES\/PMC5607825\/<\/a>) [5] arat\u0103 c\u0103 tulburarea nivelurilor de Melatonina, GABA, precum \u0219i a antioxidan\u021bilor vitamina C \u0219i Glutathion sunt direct corela\u021bi cu insomnia \u0219i alte tulbur\u0103ri legate de somn la pacien\u021bii care au suferit un accident vascular cerebral (AVC).<\/p>\n Magneziul activeaz\u0103 sistemul nervos parasimpatic, responsabil pentru dob\u00e2ndirea st\u0103rii de lini\u0219te \u0219i relaxare. Prezen\u021ba unui nivel optim de magneziu\u00a0m\u0103re\u0219te activitatea neurotransmi\u021b\u0103torului GABA<\/strong>\u00a0\u0219i ajut\u0103 la reglarea\u00a0produc\u021biei de melatonin\u0103<\/strong>, func\u021bion\u00e2nd \u00een acela\u0219i timp ca un amortizor al semnalelor sistemului nervos care men\u021bin starea de veghe.<\/p>\n \u00centr-un studiu dublu-orb asupra celor cu insomnie, suplimentarea cu melatonin\u0103 a fost eficient\u0103 pentru\u00a0reducerea laten\u021bei somnului<\/strong>\u00a0(timpul necesar adormirii) \u0219i<\/strong>\u00a0\u00eembun\u0103t\u0103\u021birea calit\u0103\u021bii somnului<\/strong>. Acest lucru a m\u0103rit vigilen\u021b\u0103 \u00een timpul zilei, f\u0103r\u0103 efecte secundare. [6] Un alt studiu controlat randomizat a ar\u0103tat c\u0103\u00a0melatonina este eficient\u0103 \u00een ameliorarea substan\u021bial\u0103 a<\/strong>\u00a0simptomelor de insomnie la 50% din grupul de studiu<\/strong>. Melatonina nu a afectat abilit\u0103\u021bile motorii a doua zi. [7]<\/p>\n Sinergia acidului gamma-aminobutiric, al\u0103turi de melatonin\u0103 \u0219i magneziu reprezint\u0103 o compozi\u021bie atent echilibrat\u0103, formulat\u0103 de\u00a0LipoCellTech™<\/strong>, Marea Britanie, iar \u00eencapsularea \u00een lipozomi naturali, de \u00eenalt\u0103 stabilitate, permit eviden\u021bierea rapid\u0103 a efectelor terapeutice.<\/p>\n Vitamine minerale, extracte naturale \u00een form\u0103 de pudr\u0103 lipozomal\u0103 pur\u0103<\/strong> Absorb\u021bia suplimentelor lipozomale este de 20 de ori mai mare dec\u00e2t \u00een cazul suplimentelor clasice. Tehnologia brevetat\u0103 LipoCellTech™, Marea Britanie, distribuit\u0103 exclusiv \u00een Rom\u00e2nia sub brandul Hypernatura\u00ae, permite ob\u021binerea unei forme unice, naturale, de lipozomi,\u00a0f\u0103r\u0103 utilizarea temperaturilor \u0219i a presiunilor \u00eenalte, f\u0103r\u0103 solven\u021bi sau ad\u0103ugare de alcool<\/strong>,\u00a0arome<\/strong>\u00a0sau\u00a0alte ingrediente inactive<\/strong>.<\/p>\n Cele mai cunoscute metode de producere a suplimentelor lipozomale utilizeaz\u0103 temperaturi \u0219i presiuni \u00eenalte, sau substan\u021be chimce. Din cauza acestui motiv ingredientele active nu r\u0103m\u00e2n intacte.<\/p>\n Tehnologia de \u00eencapsulare lipozomal\u0103\u00a0LipoCellTech™<\/strong>\u00a0permite ob\u021binerea lipozomilor printr-o metod\u0103 natural\u0103 \u0219i unic\u0103 \u00een lume.<\/p>\n Majoritatea suplimentelor sub form\u0103 de comprimate, capsule sau pudr\u0103, sunt foarte pu\u021bin absorbite de c\u0103tre corp. Ele sunt distruse \u00een mediul intestinal \u00eenainte de a ajunge la destina\u021bie.<\/em><\/strong><\/p>\n Prin \u00eenveli\u0219ul fosfolipidic, vitaminele \u0219i mineralele lipozomale sunt protejate pe m\u0103sur\u0103 ce \u00eenainteaz\u0103 prin stomac \u0219i intesitne.\u00a0Microsfera lipozomal\u0103<\/strong>, al\u0103turi de nutrien\u021bii pe care \u00eei poart\u0103 \u00een interiorul ei, ajunge intact\u0103 \u00een fluxul sanguin, dup\u0103 care\u00a0este absorbit\u0103 direct \u00een celul\u0103<\/strong>.<\/p>\n Tehnologia brevetat\u0103 copiaz\u0103 modul \u00een care organismul ob\u021bine natural propriile structuri lipozomale. Astfel\u00a0corpul<\/strong>\u00a0va recunoa\u0219te moleculele lipozomale<\/strong>\u00a0ca fiind ale sale<\/strong>, asigur\u00e2nd un grad de absorb\u021bie ce dep\u0103\u0219e\u0219te 95%. Dup\u0103 livrarea ingredientelor active c\u0103tre celule, \u00eenveli\u0219ul fosfolipidic din care este compus lipozomul se contope\u0219te cu peretele celular,\u00a0fortific\u00e2ndu-l<\/strong>\u00a0\u0219i\u00a0regener\u00e2ndu-l<\/strong>.<\/p>\n Procesul patentat de ob\u021binere natural\u0103 a lipozomilor\u00a0<\/em><\/strong>a luat na\u0219tere dintr-un studiu atent al structurilor lipidice \u0219i dezvoltarea, \u00een parcursul mai multor ani, de diferite metode de \u00eenf\u0103\u0219urare a lipidelor \u00een jurul unor enzime \u0219i molecule, astfel \u00eenc\u00e2t aceastea s\u0103 poat\u0103 fi studiate \u00een mediul lor natural cu scopul ob\u021binerii de rezultate exacte.<\/em><\/p>\n Produsele lipozomale inovatoare ale LipoCellTech™ se remarc\u0103 prin compozi\u021bia lor pur\u0103. Metoda de produc\u021bie asigur\u0103 prezen\u021ba ingredientelor pure, active \u0219i lipsa agen\u021bilor de \u00eenc\u0103rcare, antiaglomeran\u021bilor sau a conservan\u021bilor.<\/strong><\/p>\n \u00cen parcursul \u00eentregului proces brevetat de produc\u021bie se folosesc doar\u00a0ingrediente selec\u021bionate pentru puritatea lor<\/strong>. Unitatea de produc\u021bie este\u00a0certificat\u0103 GMP<\/strong>\u00a0\u0219i respect\u0103 proceduri stricte de calitate. Fiecare etap\u0103 a procesului de fabrica\u021bie este atent documentat\u0103 \u0219i testat\u0103. Cur\u0103\u021barea utilajelor de produc\u021bie LipoCellTech™ este f\u0103cut\u0103 exclusiv cu agen\u021bi de cur\u0103\u021bare organici.<\/p>\n Procesul de \u00eencapsulare lipozomal\u0103 permite trecerea intact\u0103 a substan\u021belor active prin sistemul digestiv f\u0103r\u0103 a fi afectat de sucurile gastrice, enzime digestive, s\u0103ruri biliare, duc\u00e2nd nutrien\u021bii direct c\u0103tre celulele corpului. Chemotactismul func\u021bioneaz\u0103 \u00eentr-un mod evident \u0219i permite lipozomilor s\u0103 fie atra\u0219i de celulele umane prin faptul c\u0103 sunt practic \u201ebio-identici\u201d \u0219i astfel elibereaz\u0103 ingredientele active, direct \u00een celul\u0103, \u00een organele \u021bint\u0103. Acest proces ofer\u0103 cel mai \u00eenalt nivel de biodisponibilitate.<\/p>\n Din p\u0103cate termenul\u00a0lipozomal<\/em><\/strong>\u00a0nu este protejat prin lege, astfel exist\u0103 \u0219i produse v\u00e2ndute ca fiind lipozomale dar formulele rezultate, de cele mai multe ori, nu prezint\u0103 stabilitate \u00een tractul digestiv. Majoritatea formelor \u201eliposolubile\u201d se distrug rapid \u00een procesul de digestie \u00eenainte de a avea loc absorb\u021bia lor, eliber\u00e2nd substan\u021bele nutritive \u00een intestinul sub\u021bire, de unde pot fi eliminate cu u\u0219urin\u021b\u0103 din corp \u0219i astfel nu exist\u0103 practic o diferen\u021b\u0103 fa\u021b\u0103 de forma clasic\u0103.<\/p>\n 1 capsul\u0103 pe zi, cu jum\u0103tate de or\u0103 \u00eenainte de culcare.<\/p>\n Magneziu citrat 168 mg (con\u021bine 16.8 mg magneziu), amestec lipozomal brevetat de fosfolipide ale acizilor oleic \u0219i palmitic din\u00a0semin\u021be de floarea soarelui<\/strong>\u00a0provenite din culturi cu identiate protejat\u0103 non-GMO 96.6 mg, GABA (acid gamma-aminobutiric) 56 mg, Melatonin\u0103 1.4 mg.<\/p>\n Nu con\u021bine<\/strong>: coloran\u021bi, conservan\u021bi, alcool, arome sintetice, zah\u0103r, organisme modificate genetic, amidon, gluten, deriva\u021bi din carne \u0219i lapte, drojdie, soia, sau alte ingrediente inactive.<\/p>\n Prezentare<\/strong>: flacon din sticl\u0103 brun\u0103 (singura solu\u021bie de ambalare care p\u0103streaz\u0103 nealterate calit\u0103\u021bile produsului \u0219i nu influen\u021beaz\u0103 propriet\u0103\u021bile acestuia) cu 30 capsule vegetale;<\/p>\n Produc\u0103tor<\/strong>: LipoCellTech™, Marea Britanie<\/p>\n Precau\u021bii<\/strong>:<\/p>\n Deoarece acidul gamma-aminobutiric poate produce somnolen\u021b\u0103, dup\u0103 administrare nu este indicat\u0103 conducerea de vehicule auto sau manevrarea utilajelor grele; Certificat de notificare emis de Ministerul S\u0103n\u0103t\u0103\u021bii prin CRSP Ia\u0219i \u2013 seria AD nr. 1698\/01.09.2020.<\/p>\n Unic importator \u0219i distribuitor pentru Rom\u00e2nia SC HYPERFARM SRL<\/strong><\/p>\n Referin\u021be:<\/p>\n [1<\/strong>] I.S. Shiah and N. Yatham, GABA functions in mood disorders: An update and critical review,\u00a0Life Sciences<\/em>, Vol 63(15), 1998, pp. 1289-1303. [2<\/strong>] Martin Davies, The role of GABAA receptors in mediating the effects of alcohol in the central nervous system, PubMed, 2003 (https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC165791\/<\/a>), [3<\/strong>] Giovanni Addolorato, Lorenzo Leggio, F Woodward Hopf, Marco Diana & Antonello Bonci, Novel Therapeutic Strategies for Alcohol and Drug Addiction: Focus on GABA, Ion Channels and Transcranial Magnetic Stimulation, Neuropsychopharmacology volume 37, pages163\u2013177(2012), [4<\/strong>] Neil Bernard Boyle,* Clare Lawton, and Louise Dye, The Effects of Magnesium Supplementation on Subjective Anxiety and Stress, PubMed, 2017 (https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5452159\/<\/a>). [5<\/strong>] Wei Zhang, Fang Li, and Tong Zhang, M.D., Ph.D., Relationship of nocturnal concentrations of melatonin, gamma-aminobutyric acid and total antioxidants in peripheral blood with insomnia after stroke: study protocol for a prospective non-randomized controlled trial, Neural Regen Res. 2017 Aug; 12(8): 1299\u20131307. [6<\/strong>] Patrick Lemoine, Tali Nir, Moshe Laudon, Nava Zisapel, Prolonged\u2010release melatonin improves sleep quality and morning alertness in insomnia patients aged 55 years and older and has no withdrawal effects, 21 November 2007, Journal of Sleep Research (https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1111\/j.1365-2869.2007.00613.x<\/a>), [7<\/strong>] Remy Luthringer, Muriel Muzet, Nava Zisapel, Luc Staner, The effect of prolonged-release melatonin on sleep measures and psychomotor performance in elderly patients with insomnia, PubMed, 2009 (https:\/\/pubmed.ncbi.nlm.nih.gov\/19584739\/<\/a>).<\/p>\n Tehnologie patentat\u0103 care asigur\u0103 absorb\u021bia p\u00e2n\u0103 la 99% a nutrien\u021bilor direct \u00een celulele organismului.<\/strong><\/p>\n Sinergia acidului gamma-aminobutiric, al\u0103turi de melatonin\u0103 \u0219i magneziu restabile\u0219te echilibrul neurotransmi\u021b\u0103torilor noradrenalin\u0103, dopamin\u0103 \u0219i serotonin\u0103, calmeaz\u0103 sistemul nervos, scade nivelul de stres, asigur\u0103 un somn profund, previne \u0219i ajut\u0103 \u00een tratamentul alcoolismului \u0219i afec\u021biunilor neurologice.<\/p>\n","protected":false},"featured_media":13069,"template":"","meta":{"inline_featured_image":false},"product_cat":[1502],"product_tag":[],"class_list":["post-13068","product","type-product","status-publish","has-post-thumbnail","product_cat-vitamine","first","outofstock","shipping-taxable","purchasable","product-type-simple"],"yoast_head":"\n
\n<\/strong><\/p>\nGABA influen\u021beaz\u0103 somnul<\/strong><\/h4>\n
Consumul de alcool \u0219i nivelurile GABA<\/strong><\/h4>\n
Magneziul \u0219i GABA<\/strong><\/h4>\n
Rela\u021bia Magneziu-GABA-Melatonin\u0103<\/strong><\/h4>\n
Complexul sinergic Lipozomal Sleep Formula Hypernatura\u00ae contribuie la<\/strong>:<\/h5>\n
\n
LipoCellTech™<\/strong><\/h1>\n
![\"3](\"https:\/\/www.hypernatura.com\/wp-content\/uploads\/2019\/06\/3-atribute-buline.png\")
<\/a><\/p>\n\n
Metoda folosit\u0103 de\u00a0<\/strong>LipoCellTech™\u00a0<\/strong>reproduce modelul naturii<\/strong><\/h4>\n
![\"\"](\"https:\/\/www.hypernatura.com\/wp-content\/uploads\/2019\/06\/Lipozomal-Hypernatura.png\")
<\/p>\nDe ce Lipozomal Sleep Formula Hypernatura<\/strong>\u00ae<\/strong><\/h6>\n
\n
Administrare\u00a0<\/strong>Lipozomal Sleep Formula Hypernatura<\/strong>\u00ae<\/strong>:<\/h6>\n
Compozi\u021bie per capsul\u0103<\/strong>:<\/h6>\n
\nUtilizarea de c\u0103tre femeile \u00eens\u0103rcinate sau care al\u0103pteaz\u0103 se poate face la recomandarea consultantului de specialitate;
\nAsocierea cu tratamentele alopate (ex. antidepresive, antispihotice, antihipertensive) se face doar prin recomandare \u0219i monitorizare medical\u0103;
\nA nu se l\u0103sa la indem\u00e2na \u015fi la vederea copiilor mici. A se p\u0103stra \u00een ambalajul original, la loc uscat, ferit de razele soarelui;
\nA nu se utiliza de c\u0103tre persoanele cu alergie la oricare dintre ingrediente;
\nA se p\u0103stra ferit de c\u0103ldur\u0103 \u0219i umiditate \u00een ambalajul original,
\nUn supliment alimentar nu este un substitut pentru o diet\u0103 variat\u0103 \u0219i echilibrat\u0103 \u0219i un mod de via\u021b\u0103 s\u0103n\u0103tos.
\nInforma\u021biile prezentate au scopul de a oferi suport practicienilor din domeniul s\u0103n\u0103t\u0103\u021bii. V\u0103 rug\u0103m s\u0103 urma\u021bi sfatul unui medic \u00een cazul unor probleme de s\u0103n\u0103tate.<\/p>\n![\"lipozomal](\"https:\/\/www.hypernatura.com\/wp-content\/uploads\/2019\/06\/lipozomal-caracteristici.png\")
<\/p>\n","protected":false},"excerpt":{"rendered":"\n